In situ transmission electron microscopy observations of CaCO 3 crystallization onto polysaccharide-coated nanoparticles

Key Points

• The study aims to understand how calcium carbonate forms near polysaccharides by observing the nucleation process.
• Conducted in situ observations using low-pressure transmission electron microscopy (LP-TEM)
• Analyzed the effect of macromolecular properties on crystallization
• Examined the interface between polysaccharides and the electron microscopy membrane solution
• Nucleation of calcium carbonate is favored at the interfaces of polysaccharides and the TEM membrane-solution
• Crystallization timing and size are influenced by the properties of the surrounding solution and polysaccharides.