To develop a self-powered, flexible, and biocompatible piezoelectric energy harvesting device for real-time oral health monitoring and therapeutic applications. A composite membrane was fabricated by combining polyvinylidene fluoride (PVDF) with zirconium dioxide (ZrO₂) nanoparticles (0–3.0 wt%) using electrospinning technology. The membrane was characterized morphologically, chemically, mechanically, and piezoelectrically. The resulting piezoelectric nanogenerator (PENG) was integrated into bite-force testing films, mouthguards, and aligners. Biocompatibility was assessed using CCK-8, LIVE/DEAD, immunofluorescence, and ICP-OES analyses. The addition of 1.0 wt% ZrO₂ significantly increased the β-phase content and piezoelectric output, yielding a peak voltage of 0.81 V under 0.5 MPa pressure. A two-layer mouthguard achieved up to 1.05 V, enabling real-time bite-force monitoring with excellent linear response. Biocompatibility tests confirmed no cytotoxicity, along with normal cell adhesion and proliferation. This work provides a biocompatible, self-powered piezoelectric platform that can harvest oral mechanical energy for wearable diagnostics and therapies, offering a promising strategy for advanced, real-time oral healthcare systems. • Self-powered flexible PVDF/ZrO₂ composite harvests bite force energy for oral health monitoring and wearable dental devices. • 1.0 wt% ZrO₂ addition boosts voltage to 0.81 V, two-layer mouthguard reaches 1.05 V for enhanced energy capture. • Biocompatibility tests confirm non‑toxicity and support cell adhesion for safe oral use.
Jin et al. (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: