MMP-7 deletion improves survival and electrical conduction post-MI, identifying connexin-43 as a novel substrate and implicating MMP-7 in post-MI remodeling.
MMP-7 deletion results in improved survival and myocardial conduction patterns after MI. This is the first report to implicate MMP-7 in post-MI remodeling and to demonstrate that connexin-43 is a novel MMP-7 substrate.
Lindsey et al. (Tue,) studied this question.