Does intensive lipid-lowering therapy halt the progression or induce regression of calcific aortic stenosis in patients with this condition?
Intensive lipid-lowering therapy does not appear to halt progression or induce regression of calcific aortic stenosis, though small benefits or reductions in clinical endpoints cannot be excluded.
Intensive lipid-lowering therapy does not halt the progression of calcific aortic stenosis or induce its regression. This study cannot exclude a small reduction in the rate of disease progression or a significant reduction in major clinical end points. Long-term, large-scale, randomized, controlled trials are needed to establish the role of statin therapy in patients with calcific aortic stenosis.
Cowell et al. (Wed,) studied this question.