December 16, 2005Open Access

Human Parechovirus Infections in Dutch Children and the Association between Serotype and Disease Severity

KBKimberley BenschopChildren's Mercy Hospital JSJanke SchinkelNetherlands Center for Occupational Diseases RMR. P. MinnaarAmsterdam UMC Location University of Amsterdam

Structured PICO

Is HPeV3 infection associated with increased disease severity, such as sepsis-like illness and central nervous system involvement, in neonates?

Population

Dutch young children and neonates with Human Parechovirus (HPeV) infections during the period of 2000-2005

Intervention

HPeV3 infection (exposure)

Comparator

Other HPeV serotypes

Outcome

Sepsis-like illness and central nervous system involvement

HPeV3 infection is associated with severe clinical presentations, including sepsis-like illness and central nervous system involvement, in neonates.

Abstract

We report HPeV infections in young children during the period of 2000-2005 and show an association between HPeV3 infection and sepsis-like illness and central nervous system involvement in neonates.

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Cite This Study

Benschop et al. (Fri,) studied this question.

synapsesocial.com/papers/69dd1afc0219ae88a9e52dc5 https://doi.org/https://doi.org/10.1086/498905

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