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The combination of pertuzumab plus trastuzumab plus docetaxel, as compared with placebo plus trastuzumab plus docetaxel, when used as first-line treatment for HER2-positive metastatic breast cancer, significantly prolonged progression-free survival, with no increase in cardiac toxic effects. (Funded by F. Hoffmann-La Roche/Genentech; ClinicalTrials.gov number, NCT00567190.).
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José Baselga
Université Paris-Sud
Javier Cortés
Villa Maria Hospital
Sung‐Bae Kim
Ulsan College
New England Journal of Medicine
Harvard University
Massachusetts General Hospital
Seoul National University
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Baselga et al. (Wed,) studied this question.
synapsesocial.com/papers/69dd1ef03ffc04feac1334c3 — DOI: https://doi.org/10.1056/nejmoa1113216