September 18, 2010Open Access

Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat

JVJeroen VisserUniversity Medical Center Groningen KLKaren M. LammersUniversity of Maryland, Baltimore AHAJ HoogendijkAmsterdam UMC Location University of Amsterdam

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Abstract

Improved intestinal barrier function might be an important intermediate in the prevention of autoimmune diabetes by the HC diet in DP-BB rats. Effects on tight junctions, ileal cytokines and zonulin production might be important mechanisms for this effect.

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