July 5, 2021Open Access

Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response

BTBrittany P. ToddUniversity of Iowa MCMichael S. ChimentiUniversity of Iowa ZLZili LuoUniversity of Iowa

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Abstract

Concurrent lineage-specific analysis revealed novel TBI-specific transcriptional changes; these findings highlight the importance of cell-type-specific analysis of glial reactivity following TBI and may assist with the identification of novel, targeted therapies.

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Todd et al. (Mon,) studied this question.

synapsesocial.com/papers/69dd5c394917c2595e10128c https://doi.org/https://doi.org/10.1186/s12974-021-02197-w

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