December 18, 2024Open Access

Preventive efficacy of six monthly doses of NexGard® PLUS or Simparica Trio® against a macrocyclic lactone-resistant isolate (JYD-34) of Dirofilaria immitis and of a single dose of NexGard PLUS against a susceptible isolate

JPJoseph B. PrullageBoehringer Ingelheim (United States)JFJustin FrostBoehringer Ingelheim (United States)UDUtami DiCostyUniversity of Georgia

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Abstract

The results of study 1 demonstrated that NexGard® PLUS and Simparica Trio® administered at the label dose provided comparable efficacy against a macrocyclic lactone-resistant isolate of D. immitis. The results of study 2 demonstrated that NexGard® PLUS administered once near the minimum label dose was 100% effective against a susceptible isolate.

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