Mutationsanalyse des Tyrosinkinoms bei kolorektalen Karzinomen

Key Points

Key points are not available for this paper at this time.

Abstract

Tyrosinkinasen (TKs) sind zentrale Regulatoren von Signalwegen, die Differenzierung, Transkription, Zellzyklusprogression, Apoptose, Motilität und Invasion steuern (11). Obwohl bei einigen TK-Genen in bestimmten menschlichen Krebsarten mutationale Veränderungen nachgewiesen wurden (11), ist es nicht

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Authors

Alberto Bardelli

University of Pisa

D. Williams Parsons

Baylor College of Medicine

Natalie Silliman

Howard Hughes Medical Institute

Journals

Science

Actions

Institutions

Howard Hughes Medical Institute

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Discussion

Cite this study

Bardelli et al. (Do,) haben diese Frage untersucht.

synapsesocial.com/papers/69dd67d780eea7d3f699c953 — DOI: https://doi.org/10.1126/science.1082596

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Perspectives on the development of a molecularly targeted agent· 2002 · 275 citations
Oncogenic kinase signalling· 2001 · 3,709 citations
The Protein Kinase Complement of the Human Genome· 2002 · 8,130 citations
Signaling—2000 and Beyond· 2000 · 2,580 citations
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells· 1996 · 3,656 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Perspectives on the development of a molecularly targeted agent· 2002 · 275 citations
Oncogenic kinase signalling· 2001 · 3,709 citations
The Protein Kinase Complement of the Human Genome· 2002 · 8,130 citations
Signaling—2000 and Beyond· 2000 · 2,580 citations
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells· 1996 · 3,656 citations

Mutationsanalyse des Tyrosinkinoms bei kolorektalen Karzinomen

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider