September 1, 2020Open Access

Anti-tumor Effect of Hedgehog Signaling Inhibitor, Vismodegib, on Castration-resistant Prostate Cancer

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Abstract

Vismodegib inhibited cell proliferation via apoptosis and also suppressed EMT, showing anti-tumor effects in mice. Further mechanistic studies are needed to investigate the feasibility of vismodegib for CRPC treatment.

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Ishii et al. (Tue,) studied this question.

synapsesocial.com/papers/69de6f2fbf539e2270558911 https://doi.org/https://doi.org/10.21873/anticanres.14514

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