October 24, 2019

Subclinical leaflet thrombosis is associated with impaired reverse remodelling after transcatheter aortic valve implantation

Structured PICO

Is subclinical leaflet thrombosis associated with impaired left ventricular reverse remodelling after TAVI?

Population

Patients undergoing transcatheter aortic valve implantation (TAVI)

Intervention

Transcatheter aortic valve implantation (TAVI)

Comparator

Presence versus absence of subclinical leaflet thrombosis (SLT)

Outcome

Left ventricular mass (LVM) regression / LV reverse remodelling assessed by CTsurrogate

Subclinical leaflet thrombosis after TAVI is associated with impaired left ventricular reverse remodeling, potentially hindering beneficial structural changes.

Abstract

TAVI resulted in a significant LVM regression on CT. The presence of SLT showed an inverse association with LV reverse remodelling and thus it may hinder the beneficial LV structural changes. Reverse remodelling was associated with improved long-term prognosis.

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Cite This Study

Szilveszter et al. (Thu,) studied this question.

synapsesocial.com/papers/69de820b6e50a6aba3e940c3 https://doi.org/https://doi.org/10.1093/ehjci/jez256

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