February 25, 2015Open Access

Molecular subtyping for clinically defined breast cancer subgroups

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Abstract

Gene centering is often necessary to accurately apply a molecular subtype classifier. Compared with standard gene centering, our proposed subgroup-specific gene centering produced more accurate molecular subtype assignments in a study cohort with skewed clinicopathological characteristics relative to the training cohort.

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Zhao et al. (Wed,) studied this question.

synapsesocial.com/papers/69df2b1cd9e0feb21c591eaf https://doi.org/https://doi.org/10.1186/s13058-015-0520-4

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