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Inhibition of astrocyte activation in the spinal cord by tetramethylpyrazine may have utility in the treatment of CCI-induced neuroinflammation, and our results further implicate JNK-MMP-2/9 as a novel target for the attenuation of neuropathic pain.
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Lai Jiang
University of North Carolina at Chapel Hill
Cailong Pan
Nanjing Medical University
Chaoyu Wang
Chongqing University
Journal of Neuroinflammation
SHILAP Revista de lepidopterología
Nanjing Medical University
Xuzhou Medical College
Jiangsu Cancer Hospital
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Jiang et al. (Thu,) studied this question.
synapsesocial.com/papers/69dff5856ea3fbd8f9e9bf8f — DOI: https://doi.org/10.1186/s12974-017-0947-x