What question did this study set out to answer?

To explore the potential link between chronic vagus nerve compression and gastrointestinal symptoms.

April 16, 2026

Neurogenic irritable bowel syndrome? Long-term resolution of chronic gastrointestinal stress following vagus nerve microvascular decompression: illustrative case

Key Points

To explore the potential link between chronic vagus nerve compression and gastrointestinal symptoms.
Illustrative case analysis of a patient with chronic GI distress
Examination of surgical intervention through vagus nerve microvascular decompression
Assessment of symptom resolution over a long-term follow-up period.
Significant resolution of gastrointestinal symptoms post-surgery
Identification of vagus nerve compression as a reversible cause of GI distress
Improvement in peristalsis function observed over time.

Abstract

While vagal injury (including intentionally via vagotomy) results in gastroparesis, the authors propose that chronic CN X compression may induce a "hyperactive rhizopathy" resulting in symptoms of overactive peristalsis. CN X compression may be an underrecognized, reversible etiology of chronic GI distress, and clinicians should consider the possibility of neurovascular conflict in this patient population. https://thejns.org/doi/10.3171/CASE2688.

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