What question did this study set out to answer?

This research aims to evaluate the genetic polymorphisms of specific genes in hepatocellular carcinoma.

April 16, 2026Personalized Medicine0 citations

Assessment of exonic polymorphism of IDH2 , KRAS1 , TP53 , and BRAF2 using PCR-RFLP in hepatocellular carcinoma: a case–control study from Arunachal Pradesh and Sikkim

This research aims to evaluate the genetic polymorphisms of specific genes in hepatocellular carcinoma.
Conducted a case-control study design.
Utilized PCR-RFLP to assess genetic variations.
Focused on genes IDH2, KRAS1, TP53, and BRAF2.
Sampled participants from Arunachal Pradesh and Sikkim.
Identified significant genetic variations linked to hepatocellular carcinoma.
Suggested therapeutic possibilities based on findings.

Our findings in the genetic landscape highlight the complexity of hepatocarcinogenesis but also point to potential therapeutic exploitation.

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