Histopathological Signatures Associated With Postoperative Recurrence in Pediatric Chronic Rhinosinusitis With Nasal Polyps

Key Points

• This research aims to profile histopathological features associated with recurrence in pediatric chronic rhinosinusitis with nasal polyps.
• Conducted histopathological profiling of samples from patients with chronic rhinosinusitis with nasal polyps.
• Analyzed basement membrane thickness and goblet cell counts.
• Identified potential markers for postoperative recurrence.
• Basement membrane thickening and goblet cell hyperplasia characterized the pediatric rCRSwNP.
• Goblet cell hyperplasia was found to independently predict postoperative recurrence.