Synergistic action of JNK activation and BChE inhibition: a novel anti- glioblastoma compound with neuroprotective profile

Key Points

• The aim is to investigate the dual effects of QY-54 in combating glioblastoma and improving cognitive function.
• Evaluate the effect of QY-54 on glioblastoma cell lines.
• Assess BChE inhibition and JNK pathway activation.
• Measure cognitive outcomes related to neuroprotection.
• QY-54 demonstrates significant anti-glioblastoma effects.
• Cognitive improvements noted alongside JNK activation and BChE inhibition.
• Suggests a synergistic mechanism contributing to both tumor suppression and neuroprotection.