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Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance | Synapse
April 17, 2026
Open Access
Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance
AG
Ali Gordjinejad Gordjinejad
AM
Andreas Matusch
Forschungszentrum Jülich
LH
Lea Hengstler
Forschungszentrum Jülich
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Key Points
This research investigates the impact of a single dose of creatine on cognitive performance following sleep deprivation.
Randomized controlled trial design
Participants experienced sleep deprivation
Assessment of cognitive performance through cognitive tasks before and after creatine administration
Statistical analysis to evaluate changes in performance
Creatine supplementation significantly improved reaction times in cognitive tasks
Participants demonstrated enhanced working memory performance after creatine
Marked reduction in cognitive decline was observed due to sleep deprivation
Abstract
https://www.mdpi.com/2072-6643/18/8/1192
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Gordjinejad et al. (Thu,) studied this question.
synapsesocial.com/papers/69e1cfe05cdc762e9d858eb8
https://doi.org/https://doi.org/10.34734/fzj-2026-02177