The recurrent identification of these genes underscores their potential as prognostic biomarkers and therapeutic targets, thereby contributing to a deeper understanding of immunopathological mechanisms and supporting the development of improved diagnostic tools and early intervention strategies. However, limited reproducibility across studies poses challenges for robust meta-analyses, underscoring the urgent need for standardised guidelines and protocols to improve consistency and reliability in future research.
Oliveira et al. (Wed,) studied this question.