A population‐based study exploring racial and gender inequities in polysubstance‐related deaths across the United States from 2004 to 2022

Key Points

• This research aims to analyze trends in polysubstance-related deaths by race and gender in the U.S. over an 18-year span.
• Conducted a population-based assessment of overdose deaths from 2004 to 2022
• Examined data across different racial and ethnic groups
• Focused on opioid and stimulant-related deaths
• Total overdose deaths from polysubstance use increased sharply from 2004 to 2022
• Non-Hispanic Black and Hispanic individuals experienced higher rates of increase
• Significant disparities observed in opioid-stimulant and opioid-only death profiles