What question did this study set out to answer?

The aim is to establish effective methods for isolating atazanavir from biological fluids for toxicological analysis.

April 19, 2026

Study of the possibility of isolating atazanavir from biological fluids for the purpose of chemical-toxicological analysis

Key Points

The aim is to establish effective methods for isolating atazanavir from biological fluids for toxicological analysis.
Developed liquid-liquid extraction techniques for urine, saliva, and blood plasma.
Employed thin-layer chromatography for identification of atazanavir.
Used UV spectrophotometry and high-performance liquid chromatography for quantification of the substance.
Identified optimal extraction conditions for atazanavir.
Successfully quantified atazanavir in various biological fluids using the developed methods.

Abstract

The article presents the results of developing optimal conditions for extracting atazanavir using liquid-liquid extraction from physiological fluids (urine, saliva, and blood plasma), as well as identifying and quantifying this substance in extracts using thin-layer chromatography, UV spectrophotometry, and high-performance liquid chromatography.

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Cite This Study

Illarionova et al. (Fri,) studied this question.

synapsesocial.com/papers/69e4745f010ef96374d901a9 https://doi.org/https://doi.org/10.17116/sudmed20266902132

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