Coumarin bearing triazole hybrids as cholinesterase inhibitors targeting Alzheimer's disease

Key Points

• The aim is to explore the efficacy of coumarin-triazole hybrids as cholinesterase inhibitors for Alzheimer's disease.
• Synthesis of novel coumarin-triazole hybrid compounds.
• Evaluation of the inhibitory potential on cholinesterase enzymes.
• The synthesized hybrids exhibited significant cholinesterase inhibitory activity.
• Some compounds showed stronger inhibition compared to existing treatments.