DNA aptamers that inhibit binding to human interleukin-17A and interleukin-20 | Synapse
April 22, 2026Open Access
DNA aptamers that inhibit binding to human interleukin-17A and interleukin-20
Key Points
The aim is to explore the ability of DNA aptamers to inhibit cytokine interactions involved in inflammation.
Developed DNA aptamers targeting interleukin-17 and interleukin-20.
Assessed binding interactions using biochemical assays.
DNA aptamers successfully inhibited the binding of interleukin-17.
Similar inhibition observed for interleukin-20.
Abstract
DNA aptamers can inhibit binding to cytokines interleukin-17 (IL-17) and interleukin-20 (IL-20), which play important roles in inflammatory processes and autoimmune diseases.