Rapid, intense pericholedochal fibrosis after preoperative biliary drainage: A prospective histologic study in pancreatoduodenectomy specimens

Key Points

• To investigate the impact of short-term preoperative biliary drainage on pericholedochal fibrosis in pancreatoduodenectomy specimens.
• Conducted a prospective histologic analysis of pancreatoduodenectomy specimens
• Evaluated the extent of fibrosis after preoperative biliary drainage with plastic stents
• Assessed surgical outcomes in relation to fibrosis severity.
• Rapid and intense pericholedochal fibrosis observed after stenting
• Fibrotic response stabilized soon after stent placement
• No negative impact on surgical outcomes was noted.