Composition of Gut Microbiota and Its Relationship with Inflammatory Markers in Healthy Individuals and Patients with Ulcerative Colitis or Crohn’s Disease

Key Points

• The aim is to explore the relationship between gut microbiota composition and inflammatory markers in healthy individuals and those with inflammatory bowel diseases.
• Assessment of gut microbiota in Japanese patients with ulcerative colitis and Crohn's disease
• Evaluation of specific bacterial taxa associated with inflammatory markers
• Consideration of confounding factors such as age, sex, and medication use
• Significant association found between Clostridium clusters IV and XIVa and inflammatory markers
• Potential for these bacterial taxa to serve as biomarkers for inflammatory bowel disease