Do sex and race differences affect the association of risk factors with incident ischemic stroke?
The association between risk factors and incident ischemic stroke varies significantly by age, sex, and race, suggesting that specific demographic subgroups may require earlier and more aggressive preventive strategies.
For both races, at age 45 through 64 years, women were at lower stroke risk than men, and there was no sex difference at 75 years or older; however, the sex difference pattern may differ by race from age 65 through 74 years. The association of risk factors on stroke risk differed by race-sex groups. While the need for primordial prevention, optimal management, and control of risk factors is universal across all age, racial/ethnic, and sex groups, some demographic subgroups may require earlier and more aggressive strategies.
Howard et al. (Mon,) studied this question.