A 68-year-old woman with cervical cancer and pulmonary metastases presented with limb paresthesia and pain one week after chemotherapy. Whole-body bone scintigraphy performed to evaluate for bone metastases revealed rib metastases, along with poor visualization of the right distal lower extremity, raising suspicion for possible arterial flow obstruction in the right lower limb. Further imaging confirmed extensive thrombosis in the right common iliac artery and its distal branches. This case suggests that decreased uptake in the skeletal structures and surrounding soft tissues on whole-body bone scintigraphy may indicate a risk of arterial thrombosis.
Liang et al. (Fri,) studied this question.