Antwort von Szczeklik et al. auf den Brief zum Artikel „Ivabradin bei Patienten unter nichtkardialer Operation: Eine randomisierte kontrollierte Studie"

“Ivabradine did not reduce the risk of MINS in patients undergoing noncardiac surgery. Heart-rate lowering was modest and the possible higher MINS incidence in patients with known coronary artery disease is contrary to our original hypothesis. Further research is needed to establish a method to safely control the heart's stress associated with noncardiac surgery.”