Unified Photoredox Platform for Divergent SO 2 -Capture Transformations: Substrate-Controlled Switch toward 1,4-HAT-Enabled 1,2-Hydrosulfonylation or 1,2-Sulfonylative Spirolactamization

Key Points

• To investigate a unified photoredox platform for SO2-capture transformations and their therapeutic applications.
• Utilized a photoredox strategy for SO2-capture transformations.
• Analyzed products for antibacterial and antifungal activity.
• Employed mechanistic studies including radical trapping and isotope labeling.
• Showed notable antibacterial and antifungal activity of selected products.
• Highlighted the therapeutic potential of S(VI) scaffolds in medicinal chemistry.