Chlorhexidine is extensively utilized as a skin antiseptic in routine clinical practice. In recent years, reports of life-threatening hypersensitivity reactions induced by chlorhexidine have been increasing progressively. Nevertheless, severe allergic events attributable to chlorhexidine-containing skin disinfectants are frequently misdiagnosed in clinical settings. Herein, we present a pediatric case with recurrent severe allergic reactions following exposure to chlorhexidine-based skin disinfection. This report aims to raise clinicians' awareness of chlorhexidine hypersensitivity.
Zhao et al. (Mon,) studied this question.