March 31, 2017Open Access

IL-15 sustains IL-7R-independent ILC2 and ILC3 development

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Abstract

ILC survival in vitro and compensates for IL-7R deficiency, as residual ILCs are depleted in mice lacking both molecules. Collectively, these data demonstrate that siLP ILCs are not completely IL-7R dependent, but can persist partially through IL-15 signalling.

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Robinette et al. (Fri,) studied this question.

synapsesocial.com/papers/69fdf2cf37bfdcfbd750c4e9 — DOI: https://doi.org/10.1038/ncomms14601

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Authors

Michelle L. Robinette

Brigham and Women's Hospital

Jennifer K. Bando

Stanford University

Wilbur M. Song

Washington University in St. Louis

Journals

Nature Communications

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Institutions

Washington University in St. Louis

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Building similarity graph...

Analyzing shared references across papers

IL-15 sustains IL-7R-independent ILC2 and ILC3 development

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Also consider