What question did this study set out to answer?

To evaluate the efficacy of the perfusion index as a predictor of ischemia progression in patients with peripheral arterial disease.

May 9, 2026Angiology4 citations

The Perfusion Index May be an Accurate Tool for Predicting the Progression of Ischemia in Patients with Peripheral Arterial Disease

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HKHiroyoshi KomaiKansai Medical University YKYuka KitaokaKansai Medical University NYNobuko YamamotoKansai Medical University

Key Points

To evaluate the efficacy of the perfusion index as a predictor of ischemia progression in patients with peripheral arterial disease.
Conducted a logistic regression analysis on perfusion index data among patients with peripheral arterial disease.
Evaluated the association of perfusion index values with disease progression over a 3-month follow-up period.
A perfusion index (PIave) value of < 0.27 significantly predicts disease progression (p < 0.001).
Negative predictive value of the perfusion index was found to be 98% for predicting non-progression to CLTI.

Abstract

< .001; negative predictive value: 98%). Logistic regression analysis revealed that PIave < .27 was significantly associated with disease progression. In conclusion, the PI is a simple and useful marker for accurately indicating the degree of ischemia in the toes. The PI can predict that a patient will not progress to CLTI in the next 3 months with conservative treatment and may contribute to safe follow-up.

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The Perfusion Index May be an Accurate Tool for Predicting the Progression of Ischemia in Patients with Peripheral Arterial Disease

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