Background This study provides the first comprehensive assessment of the disease burden of endocarditis in Asia, presenting epidemiological trends from 1990 to 2023. Methods Data on endocarditis for Asian countries and territories were obtained from the Global Burden of Disease Study 2023, covering incidence, prevalence, YLDs (Years Lived with Disability), YLLs (Years of Life Lost), DALYs (Disability-Adjusted Life Years), and deaths from 1990 to 2023. A secondary analysis of these data yielded the overall disease burden of endocarditis in Asia. Building on this information, we report the epidemiological trends of endocarditis across Asian countries and territories and project the disease burden for the next 17 years. Result In 2023, the total number of incident endocarditis cases in Asia was 675,481, with an ASIR of 14.57 per 100,000 population. The overall prevalence was 150,339, yielding an ASPR of 3.28 per 100,000. A total of 30,594 deaths occurred, corresponding to an ASDR of 0.67 per 100,000. DALYs amounted to 887,280, giving an age-standardized DALY rate of 18.96 per 100,000. YLLs totaled 875,657, resulting in an age-standardized YLL rate of 18.71 per 100,000. YLDs summed to 11,623, equivalent to an age-standardized YLD rate of 0.25 per 100,000. Joinpoint regression analysis revealed that from 1990 to 2023, the AAPC values for ASIR, ASPR, ASDR, and the age‑standardized YLDs rate of endocarditis in Asia were positive, whereas the AAPC values for the age‑standardized DALYs rate and the age‑standardized YLLs rate were negative. It is projected that by 2040, endocarditis will continue to impose a substantial disease burden in Asia. Conclusion In Asia, endocarditis imposes a substantial disease burden and its epidemiological trend is on the rise.
Cai et al. (Fri,) studied this question.