Correspondence on: “Bioinformatics and network pharmacology-based investigation of matrine’s therapeutic roles in breast cancer”

Key Points

• This commentary discusses the mechanisms of matrine in breast cancer, emphasizing the findings of Qu et al.
• Review of bioinformatics and network pharmacology approaches used in the original study.
• Assessment of dataset limitations and need for experimental validation.
• Suggestions for future research methodologies such as molecular dynamics and in vivo models.
• Commended the systematic methodology used in the original study.
• Highlighted limitations regarding the small dataset size and the need for pharmacokinetic considerations.
• Recommended further studies for better translational applicability.