Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis

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Abstract

to mammals. Finally, we demonstrate that both trBax and trBak BH3 peptides bind selectively to human Bcl-2 homologs to sensitize cancer cells to chemotherapy treatment.

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Popgeorgiev et al. (Wed,) studied this question.

synapsesocial.com/papers/6a02d47267f6ea5cc87565ca https://doi.org/https://doi.org/10.1126/sciadv.abc4149

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