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BACKGROUND AND PURPOSE: In intensity modulated proton therapy (IMPT), the impact of setup errors and anatomical changes is commonly mitigated by robust optimization with population-based setup robustness (SR) settings and offline replanning. In this study we propose and evaluate an alternative approach based on daily plan selection from patient-specific pre-treatment established plan libraries (PLs). Clinical implementation of the PL strategy would be rather straightforward compared to daily online re-planning. MATERIALS AND METHODS: OfA). Daily plan selection in the PL approach was based only on recomputed dose to the CTV on the rCT. RESULTS: OfA resulted in significantly improved coverage compared to PL for selected patients. CONCLUSION: OfA at limited cost in target coverage.
Oud et al. (Tue,) studied this question.
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