Alterations in left atrial volume after atrial fibrillation ablation correlated significantly with changes in circumferential reservoir strain in both paroxysmal and non-paroxysmal atrial fibrillation patients.
Observational (n=80)
No
Does atrial fibrillation ablation alter left atrial volume and two-directional reservoir function in patients with paroxysmal and non-paroxysmal atrial fibrillation?
Atrial fibrillation ablation induces acute, directionally different changes in left atrial reservoir strain between paroxysmal and non-paroxysmal AF patients, with LA volume changes correlating closely with circumferential strain.
Effect estimate: r=0.542
p-value: p=0.003
Left atrial (LA) strain, measured using speckle-tracking echocardiography (STE), is crucial for evaluating LA performance. However, alterations in longitudinal and circumferential LA reservoir function after atrial fibrillation (AF) ablation remain undefined. We aimed to examine acute changes in two-directional LA reservoir function and their relationship to those in LA volume before and after AF ablation. We quantified the maximum LA volume index (LAVImax) and longitudinal (LASr) and circumferential (LASrc) reservoir strain using 3D-STE in 80 patients (45 males) before ablation and 1 day/3 months after ablation for AF (n = 46, paroxysmal atrial fibrillation (PAF); n = 34, non-PAF). LAVImax negatively correlated with left ventricular ejection fraction (LVEF, p < 0.001), LASr (p < 0.001), and LASrc (p < 0.001) before ablation. One day after ablation, LASr (p = 0.001) decreased significantly in patients with PAF, accompanied by reduced LVEF (p = 0.043) without changes in LAVImax. In patients with non-PAF, recovery in LASrc (42 ± 82%, p = 0.006) was significant compared to LASr (11 ± 60%, p = 0.296), with a reduction in LAVImax (-8 ± 20%, p = 0.049). Delta changes in LAVImax at one day after ablation correlated with those in LASrc in patients with PAF (r = 0.323, p = 0.039) and non-PAF (r = 0.542, p = 0.003). In conclusions, acute LA reservoir strain changes detected post-ablation differed in direction between patients with PAF and those with non-PAF. Alterations in LA volume correlated well with those in the circumferential reservoir strain in both PAF and non-PAF.
Minamisaka et al. (Wed,) conducted a observational in Atrial fibrillation (n=80). Atrial fibrillation ablation vs. Baseline (pre-ablation) was evaluated on Correlation between delta changes in maximum left atrial volume index (LA VImax) and circumferential reservoir strain (LASrc) at one day after ablation in non-PAF patients (r=0.542, p=0.003). Alterations in left atrial volume after atrial fibrillation ablation correlated significantly with changes in circumferential reservoir strain in both paroxysmal and non-paroxysmal atrial fibrillation patients.