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The origin of the myeloma protein found in mice bearing the plasma cell tumor X5563 has been investigated. Specific activity-time curves of the myeloma proteins isolated from the tumor and from the plasma of these animals were compared following intravenous injection of L-lysine-C(14). The results indicate that myeloma protein is synthesized in the plasma cell tumor.
Nathans et al. (Tue,) studied this question.
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