Nuclear Magnetic Resonance (NMR) is a key tool in polymer research. It can quantify monomer uptake, track polymer degradation, and expose side reactions, additives, and impurities. Yet, much of this information, important for materials development, is hidden beneath the broad polymer signal. Here, we show how to cut through this barrier. We first rationalize established but often misunderstood relaxation methods (CPMG, PROJECT, WASTED), then introduce T2-filtered pure shift and DOSY methods, and finally, demonstrate how simple processing can strip away the polymer signal in experiments such as COSY and HSQC. This toolkit will have broad applications in identifying unwanted species, optimizing reactions, and, in general, improving product development.
Johnson et al. (Wed,) studied this question.