Designable NIR-II light triggered biocompatible Au NRs for highly efficient photothermal therapy of cervical cancer

Key Points

• The aim is to develop biocompatible gold nanoparticles for effective photothermal therapy in cervical cancer.
• Utilized seed-mediated synthesis of NIR-II-optimized Au NRs@PEG
• Administered 1064 nm laser for photothermal treatment
• Evaluated tumor accumulation and toxicity profiles
• Achieved high efficiency in inducing tumor inhibition
• Demonstrated low toxicity to non-target tissues
• Showed significant tumor accumulation of Au NRs@PEG