Ultrastructural analysis of myocardial biopsies from patients with right ventricular dysplasia showed interstitial fibrosis and modifications in action potential transmission structures.
Observational
Right ventricular dysplasia is characterized ultrastructurally by myocardial interstitial fibrosis and junctional system modifications rather than contraction apparatus defects or increased adipocytes.
Ultrastructural observations on myocardial biopsies from patients developing clinical and/or echocardiographic and haemodynamic signs of dysplasia of the right ventricle did not reveal morphological defects of the myocardiocyte contraction apparatus, but showed evidence of fibrosis of the myocardial interstitium and modifications of the structures involved in the transmission of the action potential into the cardiac cells as well as of the junctional system between them. Interstitial adipocytes and intracellular lipid droplets were not increased in number.
Roncali et al. (Sat,) conducted a observational in Right ventricular dysplasia. Ultrastructural observation of myocardial biopsies was evaluated on Ultrastructural morphological defects. Ultrastructural analysis of myocardial biopsies from patients with right ventricular dysplasia showed interstitial fibrosis and modifications in action potential transmission structures.