Cine MRI short-axis analysis showed a 55 ± 13% increase in circumferential mean peak systolic wall stress between apical and basal sections, proving insufficient for determining regional variations.
Observational (n=15)
Does the integration of short-axis and long-axis wall curvatures using cine MRI improve the determination of regional variations of left ventricular wall stress compared to short-axis analysis alone in normal volunteers?
Short-axis MRI studies alone are insufficient for determining regional variations of left ventricular wall stress, highlighting the need for integrating short- and long-axis curvatures.
Left ventricular functional abnormalities are associated with regional increases of wall stress and modifications of wall curvature. This study describes the integration of the short-axis and long-axis wall curvatures for determining peak systolic wall stress. Quantification was realized with cine magnetic resonance imaging (MRI) from the location of the endocardial and epicardial borders of the left ventricle on pairs of consecutive short-axis sections. Fifteen normal volunteers were subjected to cine MRI, and different methods of calculating peak systolic wall stress were compared. A short-axis analysis showed a 55 ± 13% increase of the circumferential mean of the peak systolic wall stress between apical and basal sections. Regarding the curvature, no significant increase of wall stress was observed except on the septal wall (31 ± 18%). Short-axis studies proved to be insufficient for determining the regional variations of left ventricular wall stress and for providing normal reference values for the location of abnormal regions in patients.
Balzer et al. (Wed,) conducted a observational in Healthy volunteers (n=15). Cine magnetic resonance imaging (MRI) vs. Different methods of calculating peak systolic wall stress was evaluated on Peak systolic wall stress. Cine MRI short-axis analysis showed a 55 ± 13% increase in circumferential mean peak systolic wall stress between apical and basal sections, proving insufficient for determining regional variations.
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