Continuous wave Doppler echocardiography accurately predicted pressure gradients across prosthetic valves, correlating closely with simultaneous catheter measurements (r=0.94 for maximal gradients).
Observational (n=36)
Effect estimate: r = 0.94 (maximal gradient), r = 0.96 (mean gradient)
Studies correlating prosthetic valve gradients determined by continuous wave Doppler echocardiography with gradients obtained by cardiac catheterization have, to date, been limited to patients with mitral and tricuspid prostheses or have compared nonsimultaneous measurements. Simultaneous Doppler and catheter pressure gradients in 36 patients (mean age, 63 +/- 13 years) with 42 prosthetic valves (20 aortic, 20 mitral, one tricuspid, and one pulmonary) were studied. Catheter gradients were obtained using a dual-catheter technique. The simultaneous pressure tracings and Doppler flow velocity profiles were digitized at 10-msec intervals to derive the corresponding maximal and mean gradients. The correlation between the maximal Doppler gradient and the simultaneously measured maximal catheter gradient was 0.94 (SEE = 6), and that between the Doppler gradient and the simultaneously measured mean catheter gradient was 0.96 (SEE = 3). There were no significant differences in correlation between gradients for the 32 mechanical valves (maximal gradients: r = 0.95, SEE = 6; mean gradients: r = 0.96, SEE = 3) and the 10 bioprosthetic valves (maximal gradients: r = 0.89, SEE = 6; mean gradients: r = 0.93, SEE = 3). In patients with mitral prostheses, Doppler gradients correlated well with the corresponding catheter gradients obtained with direct measurement of left atrial pressure (maximal gradients: r = 0.96, SEE = 2; mean gradients: r = 0.97, SEE = 1.2). A close correlation between corresponding Doppler and catheter gradients also was found in patients with aortic prostheses (maximal gradients: r = 0.94, SEE = 6; mean gradients: r = 0.94, SEE = 3). Thus, continuous wave Doppler echocardiography can accurately predict the pressure gradient across prosthetic valves.
Burstow et al. (Fri,) conducted a observational in Prosthetic heart valves (n=36). Continuous wave Doppler echocardiography vs. Cardiac catheterization was evaluated on Correlation between maximal and mean pressure gradients measured by Doppler and catheterization (r = 0.94 (maximal gradient), r = 0.96 (mean gradient)). Continuous wave Doppler echocardiography accurately predicted pressure gradients across prosthetic valves, correlating closely with simultaneous catheter measurements (r=0.94 for maximal gradients).