Factors Influencing the Cure Rate in Nephroblastoma: A review of 335 cases

Material and methodsThe patient data were obtained from hospitals in Finland, Norway, Iceland and Sweden (Table 1 ) .The series comprised 362 patients, 188 males and 174 females, admitted between 1927 and 1969 with histologically verified nephroblastoma.O n admission, 128 of the patients were under 2 years of age and 64 under one year (Fig. 1 ) ; in 3 patients the condition was noticed at birth; the oldest patient was 74 years of age.The first sign was an abdominal mass in 71 per cent of the patients, haematuria in 2 per cent, and in the rest fever, gastric symptoms or urogenital infection.All the patients were followed up.For 335 of them the follow-up time was at least 3 years, reckoned from the end of the primary treatment and these were used for the analysis of the initial factors possibly influencing the cure rate.The remaining 27 patients treated in 1968 and 1969 were controlled for less than 3 years.All the patients classed as cured had no sign of recurrence from the time of the primary treatment until the end of the investigation in December 1970.