Low-dose isoprenaline successfully prevented recurrent ventricular fibrillation and normalized the electrocardiographic pattern in 1 patient with Brugada syndrome experiencing an electrical storm.
Case Report (n=1)
Does isoprenaline prevent recurrent ventricular fibrillation in a patient with Brugada syndrome experiencing an electrical storm?
Low-dose isoprenaline successfully terminated an electrical storm and normalized the ECG pattern in a patient with Brugada syndrome.
A case of an electrical storm occurring in a patient implanted with a cardioverter-defibrillator for Brugada syndrome is reported. Recurrent ventricular fibrillation was initiated by short-coupled isolated monomorphic ventricular premature beats probably originating from the right ventricular outflow tract, associated with a manifest electrocardiographic pattern of Brugada syndrome. Infusion of atropine accelerated the heart rate but did not prevent ventricular fibrillation, however, low doses of isoprenaline quickly obviated any recurrence of ventricular fibrillation. This was associated with the disappearance of the short-coupled premature beats together with a normalization of the electrocardiographic pattern. Possible mechanisms are discussed according to the accepted pathophysiological hypothesis.
Maury et al. (Thu,) conducted a case report in Brugada syndrome with electrical storm (n=1). Isoprenaline was evaluated on Recurrence of ventricular fibrillation. Low-dose isoprenaline successfully prevented recurrent ventricular fibrillation and normalized the electrocardiographic pattern in 1 patient with Brugada syndrome experiencing an electrical storm.