Complete surgical resection of pulmonary metastases from soft tissue sarcomas yielded a 5-year overall survival of 38% and a disease-free survival of 41%.
Cohort (n=87)
Does complete resection of pulmonary metastases improve survival in patients with soft tissue sarcoma?
Complete resection of pulmonary metastases from soft tissue sarcomas yields a 5-year overall survival of 38%, suggesting it should be considered standard therapy when complete resection is predicted.
Sixty-seven of 87 patients with soft tissue sarcoma underwent complete resection of the metastases in the lung. In this retrospective study, follow-up was for a median of 24 months. The 5-year overall, crude and disease-free survival was 38%, 45%, and 41%, respectively. Twenty-seven (40%) patients developed a recurrence in the lung. Of the six prognostic variables, the only factor significantly related to disease-free survival was grade. It is concluded that surgery for lung metastases of soft tissue sarcoma should be considered as standard therapy when preoperative evaluation predicts a complete resection. By adding chemotherapy to surgery, an improvement of prognosis probably can be achieved.
Ceel et al. (Fri,) conducted a cohort in Pulmonary metastases from soft tissue sarcomas (n=87). Complete surgical resection was evaluated on 5-year overall survival. Complete surgical resection of pulmonary metastases from soft tissue sarcomas yielded a 5-year overall survival of 38% and a disease-free survival of 41%.