Epicardial unipolar electrogram recording revealed that local J-ST elevation in Brugada syndrome is related to local activation delay, an association that was attenuated by pilsicainide.
Observational
Key Teaching Points•Epicardial unipolar electrogram recording with the filter setting in the same manner as surface electrocardiograms (ECGs) could reveal the local J-ST elevation on the right ventricle in Brugada syndrome.•The type of J-ST elevation in unipolar electrodes could be related to the local activation delay in bipolar electrodes.•However, after pilsicainide administration, the association between the type of J-ST elevation and local conduction delay was attenuated. •Epicardial unipolar electrogram recording with the filter setting in the same manner as surface electrocardiograms (ECGs) could reveal the local J-ST elevation on the right ventricle in Brugada syndrome.•The type of J-ST elevation in unipolar electrodes could be related to the local activation delay in bipolar electrodes.•However, after pilsicainide administration, the association between the type of J-ST elevation and local conduction delay was attenuated.
Kataoka et al. (Sat,) conducted a observational in Brugada syndrome. Pilsicainide was evaluated on Association between the type of J-ST elevation and local conduction delay. Epicardial unipolar electrogram recording revealed that local J-ST elevation in Brugada syndrome is related to local activation delay, an association that was attenuated by pilsicainide.
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