Lymphangioleiomyomatosis with Superimposed Organizing Pneumonia Diagnosed by Transbronchial Lung Cryobiopsy: A Case Report

Key Points

• The aim is to highlight the diagnostic process for Lymphangioleiomyomatosis (LAM) amidst organizing pneumonia.
• Detailed case report of a patient with diffuse cystic lung disease and multiple alveolar opacities.
• Transbronchial lung biopsy performed showing organizing pneumonia without LAM cells.
• Transbronchial lung cryobiopsy utilized for definitive diagnosis of LAM two years after corticosteroid treatment for COP.
• Initial biopsy indicated organizing pneumonia; LAM cells were not identified.
• Corticosteroid therapy was administered for cryptogenic organizing pneumonia (COP).
• LAM was diagnosed accurately via transbronchial lung cryobiopsy after prior treatment for COP.

Abstract