Patients with non-Q-wave myocardial infarction had a significantly higher incidence of reinfarction at 6 months compared to those with Q-wave infarction (p<0.001).
Cohort (n=208)
Does non-Q-wave myocardial infarction increase the risk of adverse clinical outcomes at 6 months compared to Q-wave myocardial infarction in survivors of acute myocardial infarction?
Survivors of non-Q-wave myocardial infarction are at a significantly higher risk for early reinfarction at 6 months compared to those with Q-wave infarction, identifying them as a high-risk group despite less initial myocardial damage.
p-value: p=<0.001
A prospective study of 208 consecutive survivors of acute myocardial infarction was undertaken to determine the differences between Q- and non-Q-wave infarction, concerning data from the history, clinical course, and 6-month follow-up. There were 177 patients with Q-wave infarction and 31 patients with non-Q-wave infarction. There were no significant differences for the following variables: age, sex, diabetes mellitus, smoking, positive family history, hypertension, obesity, previous infarction, history of unstable angina, heart failure or chronic obstructive pulmonary disease (COPD), Killip class in the Coronary Care Unit (CCU), arrhythmias and conduction defects in the CCU as well as drugs used. Patients with non-Q wave infarction had a higher incidence of stable angina before the myocardial infarction and a lower value of creatine kinase (CK) and serum glutamic oxalacetic transferase (SGOT). During the 6-month follow-up, 9 cardiac deaths and 17 reinfarctions occurred, while 74 patients presented angina. There were no differences between the two groups concerning the incidence of cardiac death or angina, but patients with non-Q-wave infarction had a higher incidence of reinfarction at 6 months (p less than 0.001). We conclude that although patients with non-Q-wave myocardial infarction have a lesser degree of myocardial damage, they have a high incidence of early reinfarction which puts them in a high-risk group.
Lekakis et al. (Tue,) conducted a cohort in Acute myocardial infarction (n=208). Non-Q-wave myocardial infarction vs. Q-wave myocardial infarction was evaluated on Reinfarction at 6 months (p=<0.001). Patients with non-Q-wave myocardial infarction had a significantly higher incidence of reinfarction at 6 months compared to those with Q-wave infarction (p<0.001).